Kevin James, Sheryl Crow

Ricki Lake, Kid Rock

Craig Kilborn, Louise Smith, The Umbilical Brothers

Queen Latifah, John Popper

John McEnroe, Sharon Lawrence, Nanci Griffith

Kid Scientists, Edie Falco, Dixie Chicks

John Leguizamo, Meat Loaf

Jenna Elfman, Chris Kattan, Christine Aguilera

Heather Locklear, Keyshawn Johnson

Michael J. Fox, Heather French

Robin Williams, Norm MacDonald

Stupid Pet Tricks, Ashley Judd, Randy Travis

Mark Wahlberg, Adam Sandler, Roger Ebert

Kelly Preston, Stirling Moss, Sugar Ray

Kevin Pollak, Tom Waits

Nathan Lane, Emmylou Harris & Linda Rondstadt

Mia Farrow, Russell Crowe, Paula Cole Band

Kevin Spacey, Eurythmics

Kelsey Grammer, Rebecca Gayheart

Harrison Ford, David Bowie

Dan Quayle, Melissa Ethridge

Lili Tomlin, Leah Remini, Beth Hart

Jesse Ventura, Amy Brennamen, ZZ Top

Jack Hanna, Peter Fonda, Sting

Bruce Willis, Will Ferrell

Chazz Palminteri, Billy Blanks, Wilson Pickett

Farrah Fawcett

John Malkovich, Harland Williams

Austin Payne, Patricia Arquette, Moby

Charles Grodin, Jimmie Walker, Buena Vista Social Club

John Cusack, Bob Sarlatte, LeAnn Rimes

Martha Stewart, Martin Scorcese, Ricky Martin

Joe Torre, Denzel Washington

Meryl Streep, Natalie Merchant

Luke Perry, Jimmy Kimmel, Garbage

Lauren Holly, Jimmy Fallon, Rage Against the Machine

Bill Cosby, Milla Jovovich

Susan Sarandon, Juan Montoya, East Harlem Violinists

Regis Philbin, Mitch Hedberg

Woody Harrelson, Bobby Rahal

Don Rickles, Jane Clayson

Jack Hanna, Bob Hoskins, Melanie C

Natalie Portman, Travis Pastrana, Ted Alexandro

Stupid Human Tricks, Johnny Depp

Claudia Schiffer, Chris Cornell

Will Smith, Creed

Anthony Edwards, Yasmine Bleeth

Evander Holyfield, Ted Danson, Counting Crows

Gabriel Byrne, Mark Borchardt

Bryant Gumbel, John Carpenter, Tony Bennett

Kathie Lee Gifford, Charlotte Church

Julianna Margulies, Eric Ripert, Third Eye Blind

George Carlin, Jewel

Stupid Pet Tricks, William Baldwin

Barbara Walter, Dan Patrick, Mary J. Blige

Jenny McCarthy, Martha Stewart, Foo Fighters

Tim Robbins, Laetitia Casta, B.B. King & Dr. John

Patrick Stewart, Al Franken, Bob Marley

Geena Davis, Bill Murray, Fiona Apple

Courtney Love, Tori Murden, R.E.M.

Gwyneth Paltrow, Blondie

Danny DeVito, Harry Smith

Jim Carrey, Alanis Morrisette

Joe Breen, Jude Law

Tom Brokaw, Alex Kingston, Run DMC

Emily Watson, LL Cool J

Marv Albert, Heather Matarazzo, Bruce Henderson

Hallie Eisenberg, Jon Witherspoon, Darlene Love

Matt Damon, Q-Tip

Isabella Rossellini, Bev Tanner

Jay Thomas, Nick Nordberg

Dick Clark, Ralph Charles

Stupid Human Tricks, Kevin James, Brooklyn Philharmonic

Jeff Daniels, Jake Johannsen

Lauren Bacall, Kurt Warner

Bill Pullman, Dan Naturman

George Stephanopoulos, Sue Murphy

Edie Falco, Ray Lucas, Andy Kindler

Kate Winslet, Ice Cube

Woody Harrelson, Shawn Presser, Filter

Hillary Clinton, Art Donovan

Tom Arnold, Art Donovan, Lynryd Skynryd

Regis Philbin, Mark Borchardt

Charles Grodin, Julia Roberts, Regis Philbin

Regis Philbin, Jerry Seinfeld, Danny DeVito

Paul Schaffer, Bruce Willis, Martin Short

Regis Philbin, Bill Cosby, Sarah Jessica Parker

Paul Schaffer, Steve Martin, Billy Crystal

Paul Schaffer, Drew Barrymore, Ray Romano

David Brenner, Kathie Lee Gifford, Alec Baldwin

Tom Snyder, Norm MacDonald, Don Rickles

Tom Snyder, Mike Myers, Roseanne, Bonnie Hunt

Tom Arnold, Robin Williams, Jack Hannah

Regis Philbin, Robin Williams, Foo Fighters

Bill Cosby, Heidi Klum, Vince Carter, Dr. Paula Mahone, Dane Cook

Julia Roberts, Israel Perlman

Kathie Lee Gifford, Tom Arnold, Joy Behar, Linda Edar

John Goodman, Norm MacDonald

Drew Carey, Dolly Parton

David Brenner, Carson Daley, Aida Turturro, Gary Gulman, Ben Harper & The Innocent Criminals

Season 7

Episode 149

Talk

Comedy

Late Show with David Letterman

Season 1

Season 2

Season 3

Season 4

Season 5

Season 6

Season 8

Season 9

Season 10

Season 11

Season 12

Season 13

Season 14

Season 15

Season 16

Season 17

Season 18

Season 19

Season 20

Season 21

Season 22

David Letterman uses mature humor to appeal to his audience in this weeknight series, which gets its music from a house band led by Paul Shaffer. Among the show's most-famous segments are the Top Ten List and Stupid Pet Tricks, the latter of which subsequently led to an additional recurring segment called Stupid Human Tricks.