Jason Lee, Elton John

Justin Timberlake, Sarah Silverman

Steve Carell, Jamie Lee Curtis, Joan Jett

Teri Hatcher, Jon Heder, Kenny Chesney

Calista Flockhart, Harland Williams, Gomez

Eva Longoria, Cole and Dylan Sprouse, Death Cab for Cutie

Adrien Brody, Chef G. Garvin, Alan Jackson

Evangeline Lilly, Magic Johnson, Diana Krall

Ashton Kutcher, Jenna Fischer, Amos Lee

Jessica Simpson, Bill O'Reilly, Snow Patrol

Wanda Sykes, Chris Matthews, John Mayer

Helen Mirren, B.J. Novak, Jet

Michael Clarke Duncan, Lisa Lampanelli, Rod Stewart

Bob Newhart, Kristin Chenoweth, Camp Freddy

Jarod Miller, Bradley Whitford, Ray LaMontagne

Tina Fey, Annika Sorenstam, Fergie

Tiger Woods, Emeril Lagasse, Chingy

Arnold Schwarzenegger, Heidi Klum, Le Rêve

Sandra Bullock, Michael Caine, Chris Young

David Gregory, Ali Larter, Edie Brickell & The New Bohemians

Hugh Jackman, Tim McGraw

Jennifer Love Hewitt, Tim Burton, Barry Manilow

Annette Bening, Mad Scientist David Willey, Sarah McLachlan

Sally Field, Bug Man Ruud Kleinpaste, Kevin Federline

John Landis & The Spiridellis Brothers, JoJo

Tim Allen, 8-year-old opera singer Gwyn Mackenzie, Carrie Underwood

Roseanne Barr, Sharon Osbourne, Marilyn Manson

Emma Thompson, Spencer Breslin, Regina Spektor

Penelope Cruz, John Stamos, "Weird Al" Yankovic

Russell Crowe, Rachael Ray, Kellie Pickler

Hugh Laurie, America Ferrara, the Cheetah Girls

Courtney Love, Brad Garrett, OK Go

Ellen DeGeneres, Fred Willard, Tony Bennett

Borat, Martha Stewart, Damian Rice

Lindsay Lohan, Emmitt Smith, Army Of Anyone

Sharon Stone, Patricia Arquette, Vince Gill

Rachel Weisz, Nick Cannon, Il Divo

Jaime Pressly, Adventurer Bear Grylls, Cirque du Soleil: The Beatles - LOVE

Emilio Estevez, D.L. Hughley, Josh Groban

Kate Winslet, Wilmer Valderrama, Buddy Guy

Demi Moore, Ron Livingston, Chris Cornell

Denzel Washington, Catherine O'Hara, Jerry Lee Lewis with Kid Rock

Amazing Animals With Julie Scardina, Ellen Pompeo, Nelly Furtado

Howie Mandel, Nelly Furtado

Kristin Davis, Ralphie May

Cameron Diaz, Gwyn Mackenzie, The Wreckers

Lucy Liu, Bob Saget, Snoop Dogg

Al Gore, Karolina Kurkova, Fantasia

Morgan Freeman, Josh Duhamel, Barenaked Ladies

Sen. Barack Obama, Maggie Gyllenhaal, Taylor Hicks

Cate Blanchett, Larry the Cable Guy, Corinne Bailey Rae

Dennis Miller, LaDainian Tomlinson, K.T. Tunstall

Jack Black, Chef G. Garvin, Paulina Rubio

Mel Gibson, Bil Dwyer, Ludacris

Sylvester Stallone, Parminder Nagra, Seal

Former President Jimmy Carter, Edward Norton, Panic! At the Disco

Jamie Foxx, Brad Paisley

Dakota Fanning, Aaron Eckhart, Twisted Sister

Leonardo DiCaprio, Naomi Watts, The Goo Goo Dolls

Tobey Maguire, spider expert Jules Sylvester, Sarah McLachlan

Samuel L. Jackson, Nick Thune, Scott Weiland

Robert De Niro, Jennifer Hudson

Will Smith, Pamela Anderson, Richard Roeper, The Blind Boys of Alabama

Matthew McConaughey, Opie and Anthony, The Killers

Dustin Hoffman, Abigail Breslin, African Children's Choir

George Clooney, Maria Lark, Unwritten Law

Justin Timberlake, Masi Oka, Matisyahu

Hilary Swank, Tom Papa, Akon

Terry Bradshaw, baker Marjorie Johnson, Papa Roach

Kiefer Sutherland, Betty White, Chris Daughtry

Ben Affleck, Chris Leak, Jewel

Sen. John Edwards, Terri Irwin, Mindy Smith

Helen Mirren, Isaac Mizrahi, Los Lonely Boys

Renée Zellweger, Joy Behar, Common

Paula Abdul, D.L. Hughley, Tyrese feat. Lil Jon

Matt Lauer, John & Margaret Ragonese, The All-American Rejects

Meredith Vieira, Ryan Reynolds, Robin Thicke

James Woods, Lisa Lampanelli, Five For Fighting

Don Rickles, John Stamos, Rocco DeLuca & The Burden

Jennifer Garner, Ty Pennington, Bow Wow

Jon Cryer, Jeff Garcia, Switchfoot

Sienna Miller, Phyllis Diller, Branford Marsalis Quartet

Wanda Sykes, Sendhil Ramamurthy, The Bird And The Bee

Rebecca Romijn, Bob Saget, Rodrigo Y Gabriela

Bill Cosby, Mary Lynn Rajskub, Katharine McPhee

Diane Keaton, Ivanka Trump, The Soweto Gospel Choir

Forest Whitaker, America Ferrera, Daniel Powter

Abigail Breslin, Amazing Animals With Julie Scardina, Christina Aguilera

Cuba Gooding Jr., Miss USA Tara Conner, The Game

Clint Eastwood, Jennifer Hudson, John Waite and Alison Krauss

Penelope Cruz, Tyler Perry, James Hunter

Hugh Grant, Himalayan Bears With Julie Scardina, Norah Jones

Mark Wahlberg, Sarah Silverman, Mat Kearney

Drew Barrymore, Kyle Krichbaum, Solomon Burke

Nicolas Cage, D.J. Sampson & Sam Ballerini, The Fray

Dennis Miller, baker Marjorie Johnson, Taylor Swift

Beyoncé, Charles Barkley, Kenny Wayne Shepherd

Jim Carrey, Gov. Tom Vilsack, Dustin Kensrue

Teri Hatcher, Rhys Ifans, Omarion

Simon Cowell, Randy Jackson & Ryan Seacrest, Tiki Barber, Silversun Pickups

Season 15

President George W. Bush & Laura Bush, Ben Harper with Charlie Musselwhite

Talk

Comedy

The Tonight Show with Jay Leno

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Specials

Jay Leno hosts some of the biggest celebrities in the world.